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Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing formatIsbn:Softcover - 9783642428173 Der motus rationalis - eineThe objective of this CTMI volume is to provide readers with a foundation for understanding what ADARs are and how they act to affect gene expression and function. It is becoming increasingly apparent that ADARs may possess roles not only as enzymes that deaminate adenosine to produce inosine in RNA substrates with double stranded character, but also as proteins independent of their catalytic property. Because A to I editing may affect base pairing